Pär Nordlund : rechercher sur Z-Library

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1

The Cellular Thermal Shift Assay: A Novel Biophysical Assay for In Situ Drug Target Engagement and Mechanistic Biomarker Studies

Martinez Molina, Daniel, Nordlund, Pär

Journal:

Annual Review of Pharmacology

Année:

2016

Langue:

english

Fichier:

PDF, 1.99 MB

english, 2016

2

Horizontal Cell Biology: Monitoring Global Changes of Protein Interaction States with the Proteome-Wide Cellular Thermal Shift Assay (CETSA)

Dai, Lingyun, Prabhu, Nayana, Yu, Liang Ying, Bacanu, Smaranda, Ramos, Anderson Daniel, Nordlund, Pär

Journal:

Annual Review of Biochemistry

Année:

2019

Fichier:

PDF, 2.16 MB

2019

3

Thermofluor-based high-throughput stability optimization of proteins for structural studies

Ulrika B. Ericsson, B. Martin Hallberg, George T. DeTitta, Niek Dekker, Pär Nordlund

Journal:

Analytical Biochemistry

Année:

2006

Langue:

english

Fichier:

PDF, 374 KB

english, 2006

4

Protein production and purification

Gräslund, Susanne, Nordlund, Pär, Weigelt, Johan, Bray, James, Gileadi, Opher, Knapp, Stefan, Oppermann, Udo, Arrowsmith, Cheryl, Hui, Raymond, Ming, Jinrong

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 311 KB

english, 2008

5

Enabling IMAC purification of low abundance recombinant proteins from E. coli lysates

Magnusdottir, Audur, Johansson, Ida, Dahlgren, Lars-Göran, Nordlund, Pär, Berglund, Helena

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 579 KB

english, 2009

6

Ribonucleotide Reductases

Nordlund, Pär, Reichard, Peter

Journal:

Annual Review of Biochemistry

Année:

2006

Langue:

english

Fichier:

PDF, 839 KB

english, 2006

7

High-level expression, purification, and crystallization of recombinant rat leukotriene C4 synthase from the yeast Pichia pastoris

Anders Wetterholm, Daniel Martinez Molina, Pär Nordlund, Said Eshaghi, Jesper Z. Haeggström

Journal:

Protein Expression and Purification

Année:

2008

Langue:

english

Fichier:

PDF, 1.72 MB

english, 2008

8

The cellular thermal shift assay for evaluating drug target interactions in cells

Jafari, Rozbeh, Almqvist, Helena, Axelsson, Hanna, Ignatushchenko, Marina, Lundbäck, Thomas, Nordlund, Pär, Molina, Daniel Martinez

Journal:

Nature Protocols

Année:

2014

Langue:

english

Fichier:

PDF, 1.38 MB

english, 2014

9

Understanding transport by the major facilitator superfamily (MFS): structures pave the way

Quistgaard, Esben M., Löw, Christian, Guettou, Fatma, Nordlund, Pär

Journal:

Nature Reviews Molecular Cell Biology

Année:

2016

Langue:

english

Fichier:

PDF, 922 KB

english, 2016

10

DNA methylation holds prognostic information in relapsed precursor B-cell acute lymphoblastic leukemia

Borssén, Magnus, Nordlund, Jessica, Haider, Zahra, Landfors, Mattias, Larsson, Pär, Kanerva, Jukka, Schmiegelow, Kjeld, Flaegstad, Trond, Jónsson, Ólafur Gísli, Frost, Britt-Marie, Palle, Josefine, Fo

Journal:

Clinical Epigenetics

Année:

2018

Langue:

english

Fichier:

PDF, 648 KB

english, 2018

11

Crystal structures of the methane monooxygenase hydroxylase from Methylococcus capsulatus (Bath): Implications for substrate gating and component interactions

Amy C. Rosenzweig, Hans Brandstetter, Douglas A. Whittington, Pär Nordlund, Stephen J. Lippard, Christin A. Frederick

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

1997

Langue:

english

Fichier:

PDF, 386 KB

english, 1997

12

Mechanism of substrate dephosphorylation in low Mr protein tyrosine phosphatase

Karin Kolmodin, Pär Nordlund, Johan Åqvist

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

1999

Langue:

english

Fichier:

PDF, 244 KB

english, 1999

13

Screening for Soluble Expression of Recombinant Proteins in a 96-Well Format

Rosemarie K.C. Knaust, Pär Nordlund

Journal:

Analytical Biochemistry

Année:

2001

Langue:

english

Fichier:

PDF, 159 KB

english, 2001

14

The structure of the iron centre of ribonucleotide reductase and its implications for the formation of a stable free tyrosine radical

Pär Nordlund, Ulla Uhlin, Janos Hajdu, Hasse Eklund

Journal:

Journal of Inorganic Biochemistry

Année:

1991

Langue:

english

Fichier:

PDF, 78 KB

english, 1991

15

High resolution crystal structures of the hydroxylase protein of methane monooxygenase

Amy C. Rosenzweig, Pär Nordlund, Stephen J. Lippard, Christin A. Frederick

Journal:

Journal of Inorganic Biochemistry

Année:

1995

Langue:

english

Fichier:

PDF, 71 KB

english, 1995

16

Geometry of the soluble methane monooxygenase catalytic diiron center in two oxidation states

Amy C. Rosenzweig, Pär Nordlund, Patricia M. Takahara, Christin A. Frederick, Stephen J. Lippard

Journal:

Chemistry & Biology

Année:

1995

Langue:

english

Fichier:

PDF, 3.94 MB

english, 1995

17

Efficiency of hit generation and structural characterization in fragment-based ligand discovery

Andreas Larsson, Anna Jansson, Anders Åberg, Pär Nordlund

Journal:

Current Opinion in Chemical Biology

Année:

2011

Langue:

english

Fichier:

PDF, 617 KB

english, 2011

18

Re-engineering the diiron site in rubrerythrin towards that in ribonucleotide reductase

Fredrick deMaré, Pär Nordlund, Nishi Gupta, Neeta V. Shenvi, Xiaoyuan Cui, Donald M. Kurtz Jr.

Journal:

Inorganica Chimica Acta

Année:

1997

Langue:

english

Fichier:

PDF, 740 KB

english, 1997

19

Tyrosyl radicals in iron enzymes: Structural information from high-field EPR on frozen solutions and single crystals

Friedhelm Lendzian, Marcus Galander, Martin Högbom, Pär Nordlund, Christiane Jung, Volker Schünemann, Anne-Laure Barra

Journal:

Journal of Inorganic Biochemistry

Année:

2003

Langue:

english

Fichier:

PDF, 80 KB

english, 2003

20

Conformation of the tyrosyl radical in escherichia coli ribonucleotide reductase R2

Martin Högborn, Martin Andersson, Matthias Kolberg, Pär Nordlund, Marcus Galander, Friedhelm Lendzian

Journal:

Journal of Inorganic Biochemistry

Année:

2003

Langue:

english

Fichier:

PDF, 313 KB

english, 2003

21

An efficient and generic strategy for producing soluble human proteins and domains in E. coli by screening construct libraries

Tobias Cornvik, Sue-Li Dahlroth, Audur Magnusdottir, Susanne Flodin, Benita Engvall, Victoria Lieu, Monica Ekberg, Pär Nordlund

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2006

Langue:

english

Fichier:

PDF, 305 KB

english, 2006

22

The crystal structure of the protein YhaK from Escherichia coli reveals a new subclass of redox sensitive enterobacterial bicupins

Daniel Gurmu, Jun Lu, Kenneth A. Johnson, Pär Nordlund, Arne Holmgren, Heidi Erlandsen

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2009

Langue:

english

Fichier:

PDF, 717 KB

english, 2009

23

The structure of the PP2A regulatory subunit B56γ: The remaining piece of the PP2A jigsaw puzzle

Audur Magnusdottir, Pål Stenmark, Susanne Flodin, Tomas Nyman, Tetyana Kotenyova, Susanne Gräslund, Derek Ogg, Pär Nordlund

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2009

Langue:

english

Fichier:

PDF, 734 KB

english, 2009

24

The crystal structure of human cleavage and polyadenylation specific factor-5 reveals a dimeric Nudix protein with a conserved catalytic site

Lionel Trésaugues, Pål Stenmark, Herwig Schüler, Susanne Flodin, Martin Welin, Tomas Nyman, Martin Hammarström, Martin Moche, Susanne Gräslund, Pär Nordlund

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2008

Langue:

english

Fichier:

PDF, 337 KB

english, 2008

25

Crystal structures of oxidized dinuclear manganese centres in Mn-substituted class I ribonucleotide reductase fromEscherichia coli: carboxylate shifts with implications for O2activation and radical generation

Martin Högbom, Martin E. Andersson, Pär Nordlund

Journal:

JBIC Journal of Biological Inorganic Chemistry

Année:

2001

Langue:

english

Fichier:

PDF, 227 KB

english, 2001

26

Mechanism of methane monooxygenase – a structural and quantum chemical perspective

P. E. M. Siegbahn, Robert H. Crabtree, Pär Nordlund

Journal:

JBIC Journal of Biological Inorganic Chemistry

Année:

1998

Langue:

english

Fichier:

PDF, 260 KB

english, 1998

27

Crystal structure of the R2 subunit of ribonucleotide reductase from Chlamydia trachomatis

Pal Stenmark, Martin Högbom, Pär Nordlund, Grant McClarty

Journal:

Journal of Inorganic Biochemistry

Année:

2003

Langue:

english

Fichier:

PDF, 153 KB

english, 2003

28

The structure of human collapsin response mediator protein 2, a regulator of axonal growth

Pål Stenmark, Derek Ogg, Susanne Flodin, Alex Flores, Tetyana Kotenyova, Tomas Nyman, Pär Nordlund, Petri Kursula

Journal:

Journal of Neurochemistry

Année:

2007

Langue:

english

Fichier:

PDF, 2.07 MB

english, 2007

29

Crystal structure of the shutoff and exonuclease protein from the oncogenic Kaposi’s sarcoma-associated herpesvirus

Sue-Li Dahlroth, Daniel Gurmu, Juergen Haas, Heidi Erlandsen, Pär Nordlund

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 601 KB

english, 2009

30

Structural and functional studies of the human phosphoribosyltransferase domain containing protein 1

Martin Welin, Louise Egeblad, Andreas Johansson, Pål Stenmark, Liya Wang, Susanne Flodin, Tomas Nyman, Lionel Trésaugues, Tetyana Kotenyova, Ida Johansson, Staffan Eriksson, Hans Eklund, Pär Nordlund

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 665 KB

english, 2010

31

Three-dimensional structure of the free radical protein of ribonucleotide reductase

Nordlund, Pär, Sjöberg, Britt-Marie, Eklund, Hans

Journal:

Année:

1990

Fichier:

PDF, 813 KB

1990

32

Unusual clustering of carboxyl side chains in the core of iron-free ribonucleotide reductase

Åberg, Anders, Nordlund, Pär, Eklund, Hans

Journal:

Année:

1993

Fichier:

PDF, 406 KB

1993

33

The crystal structure of a low-molecular-weight phosphotyrosine protein phosphatase

Su, Xiao-Dong, Taddei, Niccolo', Stefani, Massimo, Ramponi, Giampietro, Nordlund, Pär

Journal:

Année:

1994

Fichier:

PDF, 739 KB

1994

34

10.1038/84117

Thunnissen, Marjolein M.G.M., Nordlund, Pär, Haeggström, Jesper Z.

Journal:

Natural Structural Biology

Année:

2001

Langue:

english

Fichier:

PDF, 2.24 MB

english, 2001

35

Structural basis for synthesis of inflammatory mediators by human leukotriene C4 synthase

Molina, Daniel Martinez, Wetterholm, Anders, Kohl, Andreas, McCarthy, Andrew A., Niegowski, Damian, Ohlson, Eva, Hammarberg, Tove, Eshaghi, Said, Haeggström, Jesper Z., Nordlund, Pär

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 846 KB

english, 2007

36

Colony filtration blot: a new screening method for soluble protein expression in Escherichia coli

Cornvik, Tobias, Dahlroth, Sue-Li, Magnusdottir, Audur, Herman, Maria Dolores, Knaust, Rosemarie, Ekberg, Monica, Nordlund, Pär

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 181 KB

english, 2005

37

Colony filtration blotting for screening soluble expression in Escherichia coli

Dahlroth, Sue-Li, Nordlund, Pär, Cornvik, Tobias

Journal:

Nature Protocols

Année:

2006

Langue:

english

Fichier:

PDF, 334 KB

english, 2006

38

The structure of Desulfovibrio vulgaris rubrerythrin reveals a unique combination of rubredoxin-like FeS4 and ferritin-like diiron domains

Nordlund, Pär, deMaré, Fredrick, Kurtz, Donald M.

Journal:

Natural Structural Biology

Année:

1996

Fichier:

PDF, 1.21 MB

1996

39

Crystal structure of a human mitochondrial deoxyribonucleotidase

Rinaldo-Matthis, Agnes, Rampazzo, Chiara, Reichard, Peter, Bianchi, Vera, Nordlund, Pär

Journal:

Natural Structural Biology

Année:

2002

Langue:

english

Fichier:

PDF, 1000 KB

english, 2002

40

Structural mechanism of allosteric substrate specificity regulation in a ribonucleotide reductase

Larsson, Karl-Magnus, Jordan, Albert, Eliasson, Rolf, Reichard, Peter, Logan, Derek T, Nordlund, Pär

Journal:

Nature Structural and Molecular Biology

Année:

2004

Langue:

english

Fichier:

PDF, 1.78 MB

english, 2004

41

Crystal Structures of Two Self-Hydroxylating Ribonucleotide Reductase Protein R2 Mutants: Structural Basis for the Oxygen-Insertion Step of Hydroxylation Reactions Catalyzed by Diiron Proteins†,‖

Logan, Derek T., deMaré, Fredrick, Persson, Bert O., Slaby, Agneta, Sjöberg, Britt-Marie, Nordlund, Pär

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 331 KB

english, 1998

42

Engineering membrane protein overproduction in Escherichia coli

Daniel Martinez Molina, Tobias Cornvik, Said Eshaghi, Jesper Z. Haeggström, Pär Nordlund, Marina Ignatushchenko Sabet

Journal:

Protein Science

Année:

2008

Langue:

english

Fichier:

PDF, 322 KB

english, 2008

43

Completing the family portrait of the anti-apoptotic Bcl-2 proteins: Crystal structure of human Bfl-1 in complex with Bim

Maria Dolores Herman, Tomas Nyman, Martin Welin, Lari Lehtiö, Susanne Flodin, Lionel Trésaugues, Tetyana Kotenyova, Alex Flores, Pär Nordlund

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 337 KB

english, 2008

44

Catalysis within the lipid bilayer—structure and mechanism of the MAPEG family of integral membrane proteins

Daniel Martinez Molina, Said Eshaghi, Pär Nordlund

Journal:

Current Opinion in Structural Biology

Année:

2008

Langue:

english

Fichier:

PDF, 2.66 MB

english, 2008

45

Structural Basis for Substrate Specificity of the Human Mitochondrial Deoxyribonucleotidase

Karin Walldén, Benedetta Ruzzenente, Agnes Rinaldo-Matthis, Vera Bianchi, Pär Nordlund

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 482 KB

english, 2005

46

Structure and function of the radical enzyme ribonucleotide reductase

Hans Eklund, Ulla Uhlin, Mathias Färnegårdh, Derek T. Logan, Pär Nordlund

Journal:

Progress in Biophysics and Molecular Biology

Année:

2001

Langue:

english

Fichier:

PDF, 2.63 MB

english, 2001

47

Structural Basis for Allosteric Substrate Specificity Regulation in Anaerobic Ribonucleotide Reductases

Karl-Magnus Larsson, Jessica Andersson, Britt-Marie Sjöberg, Pär Nordlund, Derek T Logan

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 878 KB

english, 2001

48

Crystal structure of reduced protein R2 of ribonucleotide reductase: the structural basis for oxygen activation at a dinuclear iron site

Derek T Logan, Xiao-Dong Su, Anders Åberg, Karin Regnström, Janos Hajdu, Hans Eklund, Pär Nordlund

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 1.35 MB

english, 1996

49

Crystal structure of common type acylphosphatase from bovine testis

Marjolein MGM Thunnissen, Niccolo’ Taddei, Gianfranco Liguri, Giampietro Ramponi, Pär Nordlund

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 927 KB

english, 1997

50

Structural and Functional Characterization of Two Mutated R2 Proteins of Escherichia coli Ribonucleotide Reductase

Åke Larsson, Isabel Climent, Pär Nordlund, Margareta Sahlin, Britt-Marie Sjöberg

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 682 KB

english, 1996